Dr. C. KadigamuwaSenior Lecturer (Grade II)
Email Address | : | cckadigamuwa@kln.ac.lk |
Telephone (Office) | : | +94 (0)11 2 903 edit(ext: edit) |
Telephone (Cellular) | : | +94 (0)76 981 1982 |
Office Location | : | edit |
Teaching | : | Biochemistry |
Office hours available for students. | : | 08:00 - 16:00 |
Google Scholar | Research Gate |
Research Interests:
Molecular biology, Neurochemistry, Toxicology and Cancer biology
Research Publications:
Peer reviewed publications (in refereed index journals)
Abstracted presentations
- Kadigamuwa C., Choksi S., Xu Q., Cataisson C., Greenbaum S. S., Yuspa S. H. and Liu Z. "Role of Retinoic Acid Receptor-γ in DNA Damage-Induced Necroptosis". iScience. 2019, 17, 74-86.
- Xu Q., Jitkaew S., Choksi S., Kadigamuwa C., Qu J., Choe M., Jang J., Liu C. and Liu Z. "The cytoplasmic nuclear receptor RARγ controls RIP1 initiated cell death when cIAP activity is inhibited". Nature Communication. 2017, 8, 425.
- Kadigamuwa C. C., Mapa S. T. and Wimalasena K. "Lipophilic Cationic Cyanines Are Potent Complex I Inhibitors and Specific in Vitro Dopaminergic Toxins with Mechanistic Similarities to Both Rotenone and MPP+ ". Chemical Research in Toxicology. 2016, 29(9), 1468-1479.
- Kadigamuwa C. C., Le V. Q. and Wimalasena K. "2, 2′‐ and 4, 4′‐Cyanines are transporter‐independent in vitro dopaminergic toxins with the specificity and mechanism of toxicity similar to MPP+" . Journal of Neurochemistry. 2015, 135, 755-767.
Abstracted presentations
- Kadigamuwa C., Choksi S., Xu Q. and Liu Z. (2019) The role of nuclear receptor RAR in DNA damage-induced necroptosis, 19 th annual Center for Cancer Research Fellows and Young Investigators (CCR-FYI) colloquium, National Cancer Institute (NCI), Shady Grove campus, Rockville, MD, USA.
- Kadigamuwa C. (2019) Retinoic acid receptor- and cell death, Laboratory of immune Cell Biology seminar (LICB), Center for Cancer Research (CCR), National Cancer Institute (NCI), Bethesda, MD, USA.
- Kadigamuwa C., Choksi S., Xu Q. and Liu Z. (2018) The nuclear receptor RARhas an essential role in DNA damage-induced necroptosis, 11 th annual combined retreat of Center for Cancer Research (CCR), National Cancer Institute (NCI), Frederick, MD, USA.
- Choksi S., Kadigamuwa C. and Liu Z. (2018) Cytoplasmic nuclear receptor RARcontrols RIP1 initiated cell death when cIAP activity is inhibited, Staff Scientist and Staff Clinician retreat (SSSC), Center for Cancer Research (CCR), National Cancer Institute (NCI), Bethesda, MD, USA.
- Murphy D., Kadigamuwa C., Mapa M. and Wimalasena K. (2018) Analysis of 1-methyl-4-phenylpyridinium derivatives in caenorhabtis elegans, 14th Graduate Research and Scholarly Projects Symposium (GRASP), Wichita State University, KS, USA.
- Kadigamuwa C. C. and Wimalasena K. (2015) Simple cyanines are transporter independent in vitro dopaminergic toxins with specificity of toxicity similar to MPP + , 50 th American Chemical Society (ACS) Midwest Regional Meeting. St. Joseph, MO, USA.
- Kadigamuwa C. C. and Wimalasena K. (2014) Neuronal cell toxicity of fluorescent molecular probes structurally similar to MPP + , 49 th American Chemical Society (ACS) Midwest Regional Meeting. Columbia, MO, USA.
- Kadigamuwa C. C. and Wimalasena K. (2013) Neuronal toxicity of a group of industrial chemicals similar to MPP+, 48 th American Chemical Society (ACS) Midwest Regional Meeting. Springfield, MO, USA.
- Kadigamuwa C. C. and Wimalasena K. (2013) Neuronal toxicity of 1, 1’-diethyl-2, 2’- cyanine and 1, 1’-diethyl-4, 4’-cyanine, 9th Graduate Research and Scholarly Projects Symposium (GRASP), Wichita State University, KS, USA.
- Kadigamuwa C. C. and Deeyamulla M. P. (2007) Moss (Barbula sp.) as a bioindicator of heavy metal air pollution around Sapugaskanda industrial area in Sri Lanka, Proceedings of the 63 rd Annual Sessions of Sri Lanka Association for the Advancement of Science, Colombo, Sri Lanka.
- Kadigamuwa C., Deeyamulla M. P. and Senanayake P. (2007) Accumulation of heavy metals by three moss species and selection of the best candidate as a bioindicator, Proceedings of the 63 rd Annual Sessions of Sri Lanka Association for the Advancement of Science, Colombo, Sri Lanka.